1 A good medicine tasks bitter.

2 Work has a bitter root but sweet fruit. 

3 False friends are worse than bitter enemies. 

4 Beauty may have fair leaves, but bitter fruit. 

5 Patience is bitter, but its fruit is sweet. Aristotle 

6 Bitter pills may have wholesome effort. 

7 Bitter pills may have wholesome effects. 

8 A good medicine tastes bitter.

9 Learning is a bitter root,[www.Sentencedict.com] but it bears sweet fruit. 

10 The roots of education are bitter, but the fruit is sweet. 

11 He who has not tasted bitter knows not what sweet is. 

12 Who has never tasted bitter, knows not what is sweet. 

13 That which was bitter to endure may be sweet to remember. 

14 There is nothing which has not been bitter before being ripe. 

15 He is bitter in his condemnation of terrorism.

16 The bitter winter was coming.

17 The bitter cold caused the water pipes to burst.

18 He grimaced at the bitter taste.

19 She would often romance about her bitter experiences.

20 The taste is bitter and disagreeably pungent.

21 He had grown bitter as the years passed.

22 They grew bitter and resentful.

23 He gave Helen a look of bitter reproach.

24 Although again sweet candy(sentencedict.com), also has a bitter day.

25 Good medicine for health tastes bitter to the mouth.

26 The medicine had a slightly bitter taste.

27 The bitter wind cut through his jacket.

28 I felt quite bitter about it at the time.

29 Apothecaries would not sugar their pills unless they were bitter. 

30 Sit not sad because that time a fitful aspect weareth; Patience is most bitter, yet most sweet the fruit it bearth.