1. He said the issue was not a major irritant.

2. The noise of traffic is a constant irritant to city dwellers.

3. The report is bound to add a new irritant to international relations.

4. Low flying aircraft are a constant irritant in this area.

5. Tribromoethanol has been reported to be irritant to the viscera of mice and this can cause intestinal problems and death.

6. Her elder son's wife was a long-standing irritant, like an ill-perforated toilet roll.

7. The greatest irritant most people experience in their dealings with government is the arrogance of the bureaucracy.

8. Ether is irritant to the mouse respiratory tract and can cause excessive mucous secretion.

9. He was a stock irritant, an ugly man in a shabby dressing gown over a stained shirt.

10. A long-term irritant to the police has been the ongoing allegation that some officers have been closely connected with freemasonry.

11. The rogue H has always been an irritant to those interested in the origin and meaning of place names.

12. Eventually, dealers say, the irritant is expected to be sold in retail stores and convenience markets as well.

13. My fatigue and this added irritant started to push me into a depression.

14. More, he is a severe irritant, and Adelman could put up with irritation far easier than he could a tumor.

15. Phenethylamine is also a skin irritant and possible sensitizer.

16. It may be that the itching is caused by contact with irritant material.

17. The presence of the army has been a constant irritant.

18. Castor oil comes from the bean but so does a powerful skin irritant, and a deadly poison called ricin.

19. The priest, Gleb Yakunin, long has been a vocal critic and irritant to secular as well as religious authorities.

20. It seems certain that to Modigliani she acted as stimulant, irritant and catalyst for his work.

21. Chipboard and other pressed wood products are made with a resin containing formaldehyde, an irritant and suspected carcinogen.

22. By now, an artificially cosy chat with an old school friend would have been irrelevant, even an irritant.

23. On high stools they squatted, hunched in their habitual dolour, their snouts inflamed and dripping in the irritant air.

24. They often contain toxic impurities and may be an irritant to the skin.

25. The drug war is a skirmish, the leftist gangs an irritant.

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26. Buckthorn had been bitten in the foreleg and the wound, in the manner of a rat-bite, was irritant and painful.

27. Sometimes the symptoms of a medical condition seem only an inconvenIence during the day but become a major irritant at night.

28. In this plant was a milky substance which was a drastic purge and irritant.

29. Certainly smoking stimulates mucin secretion by the respiratory tract mucosa, probably by a direct irritant effect.

30. One of these involves using the hind leg to scratch an area of skin to which an irritant has been applied.