1 If endometrial hyperplasia with atypia is diagnosed by blind biopsy, further evaluation is needed to exclude a coexistent endometrial adenocarcinoma, which is present in 25 percent.

2 Endothelial cells may be plump, but no atypia is present.

3 There is minimal mitotic activity, no atypia and no desmoplasia.

4 In addition, the lack of atypia rules out squamous cell carcinoma.

5 Angiosarcomas also show significant nuclear atypia, frequent mitoses, and will often have foci of necrosis, all features typically absent in SCH.

6 In most cases, there is minimal mitotic activity, atypia or necrosis.

7 Note the lack of cytologic atypia which is helpful in distinguishing urothelial metaplasia from high - grade PIN.

8 The atypia is degenerative and not observed in the seminal vesicles of young men.

9 Endometrial hyperplasia with atypia is a premalignant condition, preferably treated with hysterectomy.

10 The neoplastic fibroblastic cells resembled the reactive fibroblasts by containing fine chromatin and small distinct nucleoli without cellular atypia or mitotic figures.

11 Pleomorphic fibroma, a benign fibroblastic proliferation with striking nuclear atypia, is extremely rare.

12 In my opinion, the invasive pattern with isolated cells and irregular glands in stroma, fibrotic background, and the degree of cytologic atypia are sufficient for a malignant diagnosis.

13 Tight acini creates a near - solid appearance. There is no cytologic atypia. Mitotic figures are rare.

14 The glands demonstrate loss of goblet cells and hyperchromatic nuclei with inflammatory atypia.

15 The tumor is composed of intersecting bundles of spindle - shaped cells with little atypia or mitotic actiity.

16 Results:JLP and condylomata acuminata were both papillomatosis characterized by epithelial hyperplasia and thickening of prickle cell layer(stratum spinosum)with some atypia in JLP.

17 The disorder is characterized by variation in the size and shape of the proliferating glands and the potential for cytological atypia ,[www.Sentencedict.com] which may progress to endometrial cancer.

18 A large of tumor cells are scattered or clustered arrangement in the smear, nuclear were round or oval shape, basophilia and marked atypia.